MYRAMAZE^®-PURE is crafted to strengthen and deeply hydrate even the driest of scalps, offering relief and protection to consumers. This innovative solution harnesses the remarkable properties of trehalose, a water-replacement sugar derived from the “resurrection bush” Myrothamnus flabellifolia, to protect and repair the scalp’s natural barrier.

Scalp health is paramount to maintaining overall hair vitality. A healthy scalp barrier acts as a shield, locking in moisture and preventing external irritants from causing damage. However, when this barrier is compromised, it becomes vulnerable to environmental stressors and transepidermal water loss is increased. Dehydration and irritation occur, which can feel like a constant source of discomfort and trigger inflammation. MYRAMAZE^®-PURE works at the core of this problem, restoring the scalp’s protective shield and locking in moisture, ensuring a healthy and comfortable scalp.

Clinical rinse-off studies have demonstrated that MYRAMAZE^®-PURE is able to protect and strengthen the scalp barrier in deleterious conditions. By promoting NMF and ceramide production in the scalp, the active ingredient is able to reinforce the barrier structure. Studies have also shown a significant protection against scalp dehydration as well as an additional moisture push. It therefore acts as a soothing ingredient, that allows a reduction in discomfort and in scalp erythema.

In-vitro studies have revealed that MYRAMAZE^®-PURE activates multiple pathways of barrier strengthening ( Nrf-2 and autophagy activation) and soothing (NF-κB and IL-31-induced STAT3 inhibition). Furthermore, it acts as a positive allosteric modulator of the cannabinoid CB1 receptor, potentiating suppression of the inflammatory responses.

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